SCIENTIFIC ADVISORY BOARD
Allen K. Murray, Ph.D.
Allen K. Murray, Ph.D., has over 25 years of experience in fundamental research for drug discovery and drug development.
Dr. Murray started Glycozyme, Inc, a specialized contract research organization, in 1983. Prior to starting Glycozyme, Inc., Dr. Murray spent in excess of 2 years as Assistant to the Director, Research, and Development, at the Muscular Dystrophy Association. His primary role at MDA was to act as a liaison between grant applicants, grantees and the scientific, medical and Postdoctoral Fellowship advisory committees. A significant amount of Dr. Murray's time was spent administering MDA's Task Force on Drug Development, fostering basic and clinical grant applications, and monitoring project performance.
Prior to MDA, Dr. Murray was a faculty member at the University of California, Irvine in Pediatrics. Prior to this position, he was an NIH Postdoctoral Fellow in Biological Chemistry at Washington University School of Medicine.
To date, Dr. Murray's major scientific accomplishments include:
Demonstration of a correlation between cell wall glycosidases and growth rate,
Demonstration of molecular heterogeneity of the lysosomal *-glucosidase of human liver which is deficient in Type II glycogenosis,
Covalently linking the lysosomal *-glucosidase of human liver to low-density lipoprotein (LDL) for the first human trial using LDL as a carrier for enzyme replacement therapy, and
The identification of a group of glycoconjugates that function as cell wall precursors in cotton fibers and which appear to be ubiquitous throughout the plant kingdom.
This work has led to new insights to the composition and structure of cellulose, the most abundant organic compound in the biosphere and a method of "fingerprinting" materials such as textiles, derived from plant sources.
Dr. Murray's additional ongoing work involves the development of a method for the specific detection of recombinant erythropoietin (r-EPO) in biological fluids with applications including the detection of performance enhancing substances (r-EPO) in samples from athletes.